- Case Report
- Shiga toxin-associated hemolytic uremic syndrome complicated by intestinal perforation in a child with typical hemolytic uremic syndrome
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Hye Jin Chang, Hwa Young Kim, Jae Hong Choi, Hyun Jin Choi, Jae Sung Ko, Il Soo Ha, Hae Il Cheong, Yong Choi, Hee Gyung Kang
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Clin Exp Pediatr. 2014;57(2):96-99. Published online February 24, 2014
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Hemolytic uremic syndrome (HUS) is one of the most common causes of acute renal failure in childhood and is primarily diagnosed in up to 4.5% of children who undergo chronic renal replacement therapy. Escherichia coli serotype O157:H7 is the predominant bacterial strain identified in patients with HUS; more than 100 types of Shiga toxin-producing enterohemorrhagic E. coli (EHEC) subtypes have... |
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- Original Article
- Intravenous fluid prescription practices among pediatric residents in Korea
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Jiwon M. Lee, Younghwa Jung, Se Eun Lee, Jun Ho Lee, Kee Hyuck Kim, Ja Wook Koo, Young Seo Park, Hae Il Cheong, Il-Soo Ha, Yong Choi, Hee Gyung Kang
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Clin Exp Pediatr. 2013;56(7):282-285. Published online July 19, 2013
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Purpose Recent studies have established the association between hypotonic fluids administration and hospital-acquired hyponatremia in children. The present paper investigated the pattern of current practice in intravenous fluid prescription among Korean pediatric residents, to underscore the need for updated education. MethodsA survey-based analysis was carried out. Pediatric residents at six university hospitals in Korea completed a survey consisting of four questions. Each... |
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- Case Report
- A case of pseudohypoaldosteronism type 1 with a mutation in the mineralocorticoid receptor gene
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Se Eun Lee, Yun Hye Jung, Kyoung Hee Han, Hyun Kyung Lee, Hee Gyung Kang, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2011;54(2):90-93. Published online February 28, 2011
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Pseudohypoaldosteronism type 1 (PHA1) is a rare form of mineralocorticoid resistance characterized in newborns by salt wasting with dehydration, hyperkalemia and failure to thrive. This disease is heterogeneous in etiology and includes autosomal dominant PHA1 owing to mutations of the NR3C2 gene encoding the mineralocorticoid receptor, autosomal recessive PHA1 due to mutations of the epithelial sodium channel (ENaC) gene, and... |
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- Renal transplantation in a patient with Bartter syndrome and glomerulosclerosis
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Se Eun Lee, Kyoung Hee Han, Yun Hye Jung, Hyun Kyung Lee, Hee Gyung Kang, Kyung Chul Moon, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2011;54(1):36-39. Published online January 31, 2011
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Bartter syndrome (BS) is a clinically and genetically heterogeneous inherited renal tube disorder characterized by renal salt wasting, hypokalemic metabolic alkalosis and normotensive hyperreninemic hyperaldosteronism. There have been several case reports of BS complicated by focal segmental glomerulosclerosis (FSGS). Here, we have reported the case of a BS patient who developed FSGS and subsequent end-stage renal disease (ESRD) and provided... |
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- A case of Bartter syndrome type I with atypical presentations
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Eun Hye Lee, Ju Sun Heo, Hyun Kyung Lee, Kyung Hee Han, Hee Gyung Kang, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2010;53(8):809-813. Published online August 31, 2010
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Bartter syndrome (BS) is an autosomal recessively inherited rare renal tubular disorder characterized by hypokalemic metabolic alkalosis and hyperreninemic hyperaldosteronism with normal to low blood pressure due to a renal loss of sodium. Genetically, BS is classified into 5 subtypes according to the underlying genetic defects, and BS is clinically categorized into antenatal BS and classical BS according to onset... |
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- Original Article
- Polymorphisms of the NR3C1 gene in Korean children with nephrotic syndrome
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Hee Yeon Cho, Hyun Jin Choi, So Hee Lee, Hyun Kyung Lee, Hee Kyung Kang, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2009;52(11):1260-1266. Published online November 15, 2009
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Purpose : Idiopathic nephrotic syndrome (NS) can be clinically classified as steroid-sensitive and steroid-resistant. The detailed mechanism of glucocorticoid action in NS is currently unknown.
Methods : In this study, we investigated 3 known single nucleotide polymorphisms (SNPs) (ER22/23EK, N363S, and BclI) of the glucocorticoid receptor gene (the NR3C1 gene) in 190 children with NS using polymerase chain reaction-restriction fragment... |
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- Risk Factors of Urinary Tract Infections Due to Extended-spectrum β-lactamase Producing Escherichia coli in Children
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Nam Hee Kim, Jin A Lee, Yun Kyung Kim, Eun Hwa Choi, Il Soo Ha, Hoan Jong Lee, Yong Choi
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Clin Exp Pediatr. 2004;47(2):164-169. Published online February 15, 2004
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Purpose : This study was performed to identify risk factors for urinary tract infection(UTI) by extended-spectrum β-lactamase(ESBL)-producing Escherichia coli in children.
Methods : We analyzed 125 episodes of UTI which were developed in 112 children at the Seoul National University Children's Hospital from July to December 2002. Medical records of 74 episodes of UTI caused by E. coli were reviewed in... |
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- Urinary Tract Infections in Febrile Infants under Three Months of Age
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Byung Wook Eun, Yoo Mi Chung, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong, Hoan Jong Lee, Yong Choi
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Clin Exp Pediatr. 2003;46(3):265-270. Published online March 15, 2003
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Purpose : To characterize the infants under 3 months of age with urinary tract infections(UTIs), and especially patients with bacteremia or meningitis
Methods : Hospital records of all the infants under 3 months of age discharged from our hospital for 69 consecutive months with the diagnosis of initial episode of UTI were reviewed. UTI was defined when patients had fever with... |
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- Case Report
- A Case of Systemic Capillary Leak Syndrome in a Child
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Taeg Young Lee, Yoo Mi Chung, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 2002;45(10):1292-1297. Published online October 15, 2002
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Systemic capillary leak syndrome(SCLS) is a rare disorder of unknown etiology, which is characterized
by recurrent attacks of hypotension, hemoconcentration, and hypoalbuminemia. Urinary or
enteric loss of protein is not demonstrated. It is often associated with monoclonal gammopathy,
but does not manifest multiple myeloma. Since Clarkson et al. described the first case in a 34-
year-old woman, about 50 cases have been reported in... |
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- Three Cases of Urine Abnormalities Associated with Ketogenic Diet
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Hye Won Hahn, Ki Jung Kim, Il Soo Ha, Hae Il Jung, Yong Seung Hwang, Yong Choi
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Clin Exp Pediatr. 2001;44(6):709-713. Published online June 15, 2001
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Ketogenic diet is a high-fat, low carbohydrate, low protein diet used in treatment of pediatric epilepsy since the 1920s. Currently it is used primarily to treat refractory childhood epilepsy. Few serious complications caused by ketogenic diet have been reported. Short-term complications include dehydration, hypoglycemia, vomiting, diarrhea, and refusal to eat. Long-term complications include kidney stones, recurrent infections, metabolic derangement, hypercholesterolemia,... |
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- Original Article
- Factors Associated with Renal Failure in Children with Primary Vesicoureteral Reflux
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Kyung Mi Park, Kyung Hoon Paek, Jae Hong Min, Jung Su Kim, Il Soo Ha, Kwang Myung Kim, Hae Il Cheong, Hwang Choi, Yong Choi
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Clin Exp Pediatr. 1999;42(7):959-965. Published online July 15, 1999
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Purpose : The pathophysiologic mechanisms and risk factors of renal functional deterioration are still controversial. We analyzed the factors associated with renal failure in children with primary vesicoureteral reflux.
Methods : The medical records of 166 children who were diagnosed with primary vesicoureteral reflux from Jan. 1985 to Dec. 1996 in the Department of Pediatrics, Seoul National University Children's Hospital... |
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- Renal Problems in Wilson Disease
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Il Soo Ha, Jun Ho Lee, Yeon Ho Choe, Hae Il Cheong, Sei Won Yang, Young Yull Koh, Jeong Kee Seo, Yong Choi
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Clin Exp Pediatr. 1999;42(6):817-824. Published online June 15, 1999
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Purpose : Wilson disease is a hereditary metabolic disorder characterized by an accumulation of copper in tissues which sometimes results in renal problems. This study was performed to evaluate the prevalences of the renal problems in Wilson disease and related risk factors.
Methods : In 31 patients with Wilson disease, we looked for renal problems by history taking, physical examination... |
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- Case Report
- Two Cases of Oculocerebrorenal Syndrome of Lowe
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So Won Kim, Young Suk Yu, In-One Kim, Hae Il Cheong, Yong Seung Hwang, Yong Choi
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Clin Exp Pediatr. 1999;42(3):419-423. Published online March 15, 1999
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Oculocerebrorenal syndrome of Lowe(OCRL) is a rare X-linked disorder characterized by congenital cataract(oculo-), hypotonia, developmental delay, cognitive impairment(cerebro-), renal tubular dysfunction(renal), and growth retardation. Recently, the defective gene, OCRL-1 gene encoding [PtdIns(4,5)P2] 5-phosphatase, was cloned with mutations identified in patients. Although there have been about 200 cases of OCRL reported in English literature, only three reports have been published in... |
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- Original Article
- Type I Vitamin D Dependent Rickets
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Soo Ja Hwang, Jung Soo Kim, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1998;41(7):877-882. Published online July 15, 1998
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Purpose : Vitamin D dependent rickets(VDDR) is a rare, autosomal recessively transmitted disorder characterized by hypocalcemia, hypophosphatemia, increased alkaline phosphatase, secondary hyperparathyroidism and many other clinical features. Type Ⅰ VDDR arises from primary deficiency in the renal 1α-hydroxylase that produces 1,25(OH)2D3. So patients with type I VDDR require life long administration of vitamin D.
Methods : There had been 6 children(4... |
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- A Case of Successful Treatment of Pulmonary Alveolar Hemorrhage with Plasmapheresis in Child with Systemic Lupus Erythematosus
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Jae Hong Min, Kyung Hoon Paek, Kyung Mi Park, Jin Soon Hwang, Jung Sue Kim, Il Soo Ha, Hae Il Cheong, Kyou Seup Han, Yong Choi
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Clin Exp Pediatr. 1998;41(7):974-978. Published online July 15, 1998
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Seoul National University College of Medicine, Seoul, Korea
Pulmonary hemorrhage is a rare but possibly fatal complication of systemic lupus erythematosus(SLE). We report a case of massive pulmonary hemorrhage in a 14-year-old boy recently diagnosed as SLE. He developed massive pulmonary hemorrhage during the courses of i.v. methylprednisolone pulse therapy, and did not respond to i.v. cyclophosphamide. However, he rapidly... |
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- The Efficacy of Fetal Ultrasonography and Postnatal Abdominal Ultrasonography for the Diagnosis of Neonatal Abdominal Mass
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Hee Eun Lee, Ee Kyung Kim, Hee Seok Kim, Yun Kyoung Lee, Chan Hwu Park, Kyung Ran Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Gui Won Park, Hwang Choi, Yong Choi, Chong Ku Yun
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Clin Exp Pediatr. 1998;41(3):299-306. Published online March 15, 1998
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Purpose : Most neonatal abdominal masses are benign in nature, but early detection and management is important to avoid the development of complications. So, we studied the causes of neonatal abdominal masses and the efficacy of ultrasonography for early detection and diagnosis.
Methods : We reviewed 36 newborn infants with abdominal masses who had been admitted to the nursery and Neonatal... |
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- Case Report
- A Case of Congenital Nephrotic Syndrome due to Diffuse Mesangial Sclerosis
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Jung-Jin Yu, Dong Kyu Jin, Hae Il Cheong, Hyun Soon Lee, Yong Choi
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Clin Exp Pediatr. 1998;41(3):415-419. Published online March 15, 1998
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Diffuse mesangial sclerosis(DMS) is one of the underlying pathology of congenital and infantile nephrotic syndrome. Infants with DMS develop nephrotic syndrome before 2 years of age and progress to end stage renal disease within 3 years of age. The authors experienced a case of isolated DMS in a 4-month-old male infant who had nephrotic syndrome for 1 month. The diagnosis... |
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- Original Article
- Longterm Follow-up of Autosomal Recessive Polycystic Kidney Disease
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June Huh, Il Soo Ha, Hae Il Cheong, Jeong Kee Seo, Yong Choi
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Clin Exp Pediatr. 1998;41(12):1693-1699. Published online December 15, 1998
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Purpose : This study was aimed to assess the clinical manifestations and courses of autosomal recessive polycystic kidney disease(ARPKD).
Methods : The medical records of 10 children diagnosed as infantile or juvenile ARPKD at Seoul National University Children's Hospital between January, 1984 and December, 1996, were reviewed, retrospectively.
Results : The average age at diagnosis was 3 8/12 years(4months-7 3/12 years)... |
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- Long-term Follow-up Study of Children with Minimal Change Nephrotic Syndrome
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Jung Sue Kim, Hae Il Cheong, Hyun Soon Lee, Yong Choi
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Clin Exp Pediatr. 1998;41(12):1675-1684. Published online December 15, 1998
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Purpose : Most of childhood MCNS has a long disease course with frequent relapses. This study was designed to analyze the long-term clinical course of childhood MCNS, focusing at relapsing pattern, treatment response and complications.
Mothods : The medical records of 137 children with biopsy-proven MCNS observed during 1976 ti 1996 were analyzed retrospectively. They were classified as initial responders(111 patients,... |
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- Case Report
- Three Cases of Cardiac Arrythmias Associated with Intravenous Methylprednisolone Pulse Therapy
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Jun Ho Lee, Jun Huh, Myung Dong Shin, Dong Kyu Jin, Il Soo Ha, Hae Il Cheong, Chung Il Noh, Yong Choi
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Clin Exp Pediatr. 1997;40(3):393-407. Published online March 15, 1997
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Methylprednisolone(MP) is administered by means of intravenous pulse therapy especially in the patients with focal segmental glomerulosclerosis(FSGS). There have been reports of its complications in a few increasing frequency. We experienced three cases of cardiaccomplications during intravenous pulsetherapy.Therewere onecaseof2¡ÆA-V block(Mobitztype I) and two cases of bradycardia and hypotension. In the former,2¡ÆA-V block in the first case deveoloped 45 hours after... |
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- Original Article
- The Prevalence of A985G Mutation in Medium Chain Acyl-Coenzyme A Dehydrogenase(MCAD) Gene in Neonates Determined from Guthrie Card
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Baeck Hee Lee, Hye Won Park, Moon Soo Park, Ho Jin Park, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 1997;40(12):1645-1650. Published online December 15, 1997
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Purpose : Medium chain acyl-CoA dehydrogenase(MCAD) deficiency is an autosomal recessive
disoder of β oxidation of fatty acids and characterized by episodic hypoglycemia, vomiting,
convulsion, encephalopathy, apnea, and sudden death related to fasting or infection resembling Reye
syndrome or sudden infant death syndrome. In acute stage, mortality rate is very high and
survivors have significant risk of developmental disability and chronic somatic illness. However,... |
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- Primary Distal Renal Tubular Acidosis in Children
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Byoung Chul Kang, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1996;39(7):987-996. Published online July 15, 1996
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Purpose : This study was designed to examine the clinical characteristics and the effect of
treatment in children with primary distal renal tubular acidosis (dRTA).
Methods : Medical records of 4 children diagnosed as dRTA at Seoul National University
Children's Hospital were reviewed, and the clinical manifestations, laboratory findings, diagnostic
criteria and effects of treatments were investigated.
Results : All cases presented with growth retardation.... |
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- Case Report
- A Case of Mauriac's syndrome
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Se Young Kim, Choong Ho Shin, Il Soo Ha, Hae Il Cheong, Sei Won Yang, Yong Choi, Hyung Ro Moon
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Clin Exp Pediatr. 1996;39(7):1020-1024. Published online July 15, 1996
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Mauriac's syndrome was described in the 1920s, as a triad of poorly controlled insulin
dependent diabetes mellitus, profound growth retardation, and hepatomgaly. Following the wide
availability of insulin and intensification of diabetic control, this entity has become quite rare. A
9-year-old female child was transferred to pediatric OPD of SNUCH because of hyperglycemia,
short stature, and visual disturbance. Five years prior to admission, she... |
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- Original Article
- Studies on the Distribution of Percentiles of Skinfold Thickness and Body Mass Index among Adolescents in Seoul
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Jae Sung Ko, Kang Mo Ahn, Yon Ho Choe, Eun Hwa Choi, Yong Choi, Yoon Ok An
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Clin Exp Pediatr. 1996;39(6):773-779. Published online June 15, 1996
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Purpose : With development of socioeconomic status, the prevelance of adolesecnt
obesity, which is a risk factor for cardiovascular disease, is increasing. Skinfold and body mass index are indirectly used measurement of obesity in clinical and epidemiologic studies. Triceps skinfold, subscapular skinfold and body mass index were measured in adolescents aged 12 to 17. Percentile values by age and sex and... |
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- Case Report
- Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child
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Ran Lee, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1996;39(5):722-726. Published online May 15, 1996
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Antiphospholipid syndrome is a thrombotic disorder and the serologic marker of the
syndrome is antiphospholipid antibody(lupus anticoagulant, anticardiolpin antibody, or both). In a 13-year-old girl who presented with dyspnea, pulmonary embolism and
femoral vein thrombosis were demonstrated by lung scan and abdominal ultrasonography.
She had 3 out of 11 criteria for the diagnosis of SLE, such as thrombocytopenia, positive antinuclear antibody, low C3... |
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- Isolated Splenic Infarction in a Girl with Systemic Lupus Erythematosus
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Kyung Ran Park, Hee Eun Lee, Yun Ae Jeon, Il Soo Ha, Hae Il Cheong, Joong Gon Kim, Yong Choi
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Clin Exp Pediatr. 1996;39(4):562-566. Published online April 15, 1996
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Splenic infarction is a rare disease and usually detected as a complication of SBE, atrial fibrillation, hemoglobinopathy, or myeloproliperative disorders. Although thrombotic event, such as deep vein, cerebral or renal thrombosis, is a frequent complication of SLE, there have been only a couple of cases documenting splenic infarction complicated in SLE. This is, to our knowledge, the first case report... |
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- Original Article
- Clinicopathological Study about Childhood Primary Nephrotic Syndrome Resistant to 4-week Daily Steroid Therapy
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Jung Sue Kim, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1996;39(12):1729-1735. Published online December 15, 1996
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Purpose : Steroid-resistant nephrotic syndrome in children is difficult to manage and tends to
progress to chronic renal failure. We studied clinicopathological correlations in primary nephrotic
syndrome in children resistant to 4-week daily steroid therapy.
Methods : Among children who had been admitted to Seoul National University Children's
Hospital during the period between Oct. 1985 and Jul. 1995 and diagnosed as primary nephrotic
syndrome, 87... |
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- Acute Hemorrhagic Cystitis(AHC) in Children -Etiology and Clinical Characteristics-
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Jin Won Pyo, Eun Hwa Choi, Jin Young Park, Hoan Jong Lee, Hae Il Cheong, Il Soo Ha, Yong Choi, Kwang Myung Kim, Hwang Choi, Je Geun Chi
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Clin Exp Pediatr. 1995;38(2):207-215. Published online February 15, 1995
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Purpose : AHC characterized by sudden onset of gross hematuria, dysuria and frequency oc curs in children and young adults as a self-limited disease that should be differentiated from se rious renal disorders. We have performed this study to establish the cause and characterize the clinical features of this illness in Korean children.
Methods : 19 cases collected prospectively for 30... |
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- Case Report
- Cystinuria 3 Cases
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Ji Eun Choi, Bo Young Yun, Hae Won Park, Jae Hong Park, Il Sue Ha, Hae Il Jeong, Yong Choi, Hwang Choi, In Won Kim
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Clin Exp Pediatr. 1995;38(2):245-251. Published online February 15, 1995
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We report three cases of cystinuria, presenting with urinary stones. A 2-year-old girl presented with urinary difficulty, hematuria, dysuria of sudden onset, and her 7-month-old younger brother also was presented with urinary difficulty, irritability on urination & stone passage.
Other 6-month-old boy was admitted due to sudden onset anuria. They had radioopague renal & ureter stones and stone analysis revealed mixed... |
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- Recurrent Hematuria due to Renal Hypouricemia
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Kyu Young Kim, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1995;38(1):129-132. Published online January 15, 1995
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A marked low concentration of serum uric acid(0.7-1.2mg/dl) was detected in a 14-year-old boy with recurrent episodes of gross hematuria. The hypouricemia accompanied with a markedly increased urinary clearance of uric acid (32.6-56.0ml/min), which was only minimally changed after both the administration of pyrazinamide, and inhibitor of the renal tubular secretion of uric acid, and the administration of probenecid, and... |
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- Original Article
- Pheochromocytoma in Children
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Tae Sue Ha, Jae Hong Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hyung Ro Moon, Gui Won Park
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Clin Exp Pediatr. 1994;37(7):961-968. Published online July 15, 1994
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We Reviewed 10 hypertensive children with pheochromocytoma retrospectively and the following results were obtained.
1) Out of 10 patients, 7 were male and 3 female. Age ranged from 5.5 years to 13.8 years and their median age was 9.9 years.
2) They complained of sweating, lethargy, headache, or chest pain and so on, Hypertension were noticed in all patients. Heart murmurs were... |
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- A Clinical Observation on Lupus Nephritis in Children
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Kang Mo Ahn, Jae Sung Ko, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hee Joo Kim
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Clin Exp Pediatr. 1994;37(6):842-849. Published online June 15, 1994
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We reviewed the clinical features, histrologic patterns and clinical courses of 30 children with lupus nephritis retrospectively, and the results were summerized as follows;
1) The male to female ratio was 1:2.8, and the mean age at the onset was 108/12 years.
2) The clinical symptoms were diverse, and malaise, weight loss, anorexia, fever and malar rash were the most frequent findings.
3)... |
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- Hypophosphatemic Rickets
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Jae un, June Huh, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1994;37(3):376-382. Published online March 15, 1994
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The clinical data of 27 patients with hypophosphatemic rickets treated with phosphate and 1 α-hydroxyvitamin D were analysed retrospectively. The median age at diagnosis was 4 years, and the main clinical manifestations were bowleg and short stature. Among total 24 families, 5 families(21%) had X-linked dominant mode of inheritance, 1 family (4%) had autosomal dominant mode and 17 families (71%)... |
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- Serum Alkaline Phosphatase Activity after Intravenous Administration of Albumin Preparation
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June Huh, Kang Mo Ahn, Ja Wook Koo, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1993;36(6):830-836. Published online June 15, 1993
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Serum alkaline phosphatase(AP) activity is elevated in hepatobiliary disease, bone disease, pregnancy and certain neoplasms. Recently we experienced marked elevation of serum AP activity after administration of ablumin preparation in nephrotic patients who suffered from hypovolemic symptoms. So serum AP activity and the isoenzymes in the albumin preparations & patient뭩 serum after the administration of albumin preparation were studied. Serum... |
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- Nephrotic Syndrome under 2 Years of Age
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Jae Sung Ko, Kang Mo Ahn, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1993;36(10):1395-1401. Published online October 15, 1993
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There had been total 20 patients with early onset (4 months~2 years) primary nephrotic syndrome in the Deparment of Pediatrics, Seoul National University Children's Hospital, during the period from March 1987 to February 1993. We analysed clinical courses, response to treatment, pathological findings and prognosis of the patients And the results were as follows;
1) The initial responders to steroid treatment... |
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- Acute Renal Failure Following Cardiac Surgery
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Kang Yong Park, Yeon Ho Choi, Tae Sun Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Joon Ryang Rho
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Clin Exp Pediatr. 1992;35(9):1198-1209. Published online September 15, 1992
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A retrospective study of 452 patients who undertook cardiac surgery was performed to determine the pevalence, etiology, and clinical features of postoperative acute renal failure(ARF). The overall incidence of ARF following cardiac surgery was 4.65%(21/452). The incidence of ARF following open heart surgery(OHS) was 5.11%, and that following closed heart surgery was 2.50%. Preoperactive risk factors noted in the development... |
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- Acquired Renal Cystic Disease in Childhood Chronic Renal Failure
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Tae Sun Ha, Seong Hoon Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Woo Sun Kim, Kim In One
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Clin Exp Pediatr. 1992;35(8):1044-1050. Published online August 15, 1992
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The authors evaluated 19 childrenwith chronic renal failure patients diagnosed and followed up at the Department of Pediatrics, Seoul National University Hospital for the detection of acquired renal cystic disease (ARCD) with two radiologists by the means of ultrasonography.
The results were as follows:
1) Of the 19 patients, male to femals ratio was 14:5 and of them, hemodialysis and peritoneal dialysis... |
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- A Clinical Aspect of the Hemolytic Uremic Syndrome
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Hye Won Park, Tae Sun Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1992;35(7):909-920. Published online July 15, 1992
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We reviewed the medical records of 14 children (8 girls, 6 boys), diagnosed as hemolytic uremic syndrome at Seoul National University Children뭩 Hospital from 1981 to 1990. The age at presentation ranged from 1 month to 10 years, with a mean age of 2.7 years. Only eight (57.1%) of the children had diarrheal prodrome and five (35.7%) had grossly bloody... |
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- Growth Promoting Effect of Recombinant methionyl-Growth Hormone in Children with Chronic Renal Failure
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Heon Seok Han, Yong Choi, Hyung Ro Moon
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Clin Exp Pediatr. 1992;35(10):1355-1360. Published online October 15, 1992
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The authors studied the growth-promoting effect of yeast-derived methionyl-hGH in short statured children with uremic chronic renal failure.
The subjects were prepubertal chronic renal insufficient patients whose height standard deviation scores were below -2.0. Two boys and two girls participated in this study. Chronic renal insufficiency was the only cause for the short stature.
HGH was given to the subjects in dose... |
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- Production and characterization of monoclonal antibodies against human albumin.
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Ja Wook Koo, Dong Kyu Jin, Yong Choi, Kwang Wook Ko, Suhnggwon Kim, Jung Sang Lee, Chung Gyu Park, Chang Yong Cha
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Clin Exp Pediatr. 1991;34(8):1070-1079. Published online August 31, 1991
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Hybridoma technology를 이용하여 human albumin에 선택적으로 반응하는 4 종류의 단세포군 항
처 1(HSA-1,HSA-2, HSA-3, HSA-4) 를 개발하였다. 단세포군의 isotype 및 subclass를 효소 결합
면역 측정법으로 검색한 결과 IgGi 이었다.
단세포군 항체 HSA-1 을 제외한 HSA-2, HSA-3, HSA-4 모두 human albumin에 선택적으로 반
응함을 효소 결합면역 측정 법과 Western blot immunoassay로 알아내 었다.
HSA-1, HSA-2, HSA-3는 albumin의 reduction 여부와 관계 없이 albumin molecule과 반응하였
으나,HSA-4는 albumin을 reduction하지... |
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- Acute renal failure with back pain after exercise.
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Hae Jung Park, Mi Jung Kim, Dong Kyu Jin, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jung Mi Park, Kyung Mo Yeun
-
Clin Exp Pediatr. 1991;34(6):863-868. Published online June 30, 1991
-
|
We have experienced one case of acute renal failure without clinical rhabdomyolysis characterized
by preceding exercise and back pain. This patient showed patch renal increased uptakes in bone scan
with 99mTechnetium-methylene diphosphonate, and delayed wedge-shaped contrast enhancements in
renal computed tomography. These findings can be explained by focal renal vasoconstriction of
interlobar arteries or arcuate arteries, which may be considered as one of the... |
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-
- The incidence of complications in severely obese children.
-
Dong Hwan Lee, Chong Guk Lee, Chul Lee, Yong Seung Hwang, Sung Ho Cha, Yong Choi
-
Clin Exp Pediatr. 1991;34(4):445-453. Published online April 30, 1991
-
|
The measurement of body weight, height and blood pressure, urine sugar, oral glucose tolerance
test, S-GOT, S-GPT, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol tests were made
in 324 severely obese elementary, middle and high school students (218 boys and 106 girls) to know the
incidence of complication in these children. .
The results were as follow:
1) S-GOT or S-GPT were increased abnormally in 38.3% and fatty livers were... |
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-
- A clinical study of continuous ambulatory peritoneal dialysis in childhood.
-
Tae Sun Ha, Hye Won Park, Ja Wook Koo, In Seok Lim, Hae Il Cheong, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1991;34(3):363-370. Published online March 31, 1991
-
|
A retrospective analysis of clinical with findings in 24 children continuous ambulatory peritoneal
dialysis (CAPD) who were admitted to the Department of Pediatrics, Seoul National University
Children’s Hospital from March, 1987 till August, 1990 was performed and the results were as follows;
1) The male to female ratio was 16:8, and the age distribution at the beginning of CAPD was from
59 days to 16.5... |
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-
- A case of hypomelanosis of Ito accompanying ureteral duplication and hypomelanotic scalp hair.
-
Dong Woo Son, Beom Soo Park, Heon Seok Han, Hae Il Jung, Yong Choi, Hyung Ro Moon, Seon Hoon Kim, Hwang Choi
-
Clin Exp Pediatr. 1991;34(2):281-286. Published online February 28, 1991
-
|
Hypomelanosis of Ito (incontinentia pigmenti achromians) is a cutaneous abnormality consisting of
bizarre, whorly, linear, or patchy hypopigmentation over variable portion of body surface. Multiple
assocaited defects in other systems occur in three quarters of the affected individuals. Most common-
ly, the central nervous system, eye, and musculoskeletal structures are involved. It is suggested that
the cutaneous abnormality, which is often detectable at birth... |
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-
- A comparison between remission and nonremission groups of hepatitis B virus-associated membranous nephropathy in children.
-
Kang Yong Park, Hye Won Park, Yon Ho Choe, Tae Sun Ha, Il Soo Ha, Yong Choi, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
-
Clin Exp Pediatr. 1991;34(11):1512-1518. Published online November 30, 1991
-
|
We analyzed medical records of 35 patients with Hepatitis B virus-associated Membranous
Nephropathy proven by kidney biopsy at SNUCH from Jan. 1975 to Jun. 1990. Clinical presentation,
laboratory and pathologic findings were compared between remission group (who are free of
proteinuria and edema in current status) and nonremission group (who have either proteinuria or
edema).
Age at onset was younger in remission group (4.51 ±2.93... |
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-
- IgA Nephropathy in Childhood.
-
Yong Choi, Dong Woo Son, Ja Wook Koo, Dong Kyu Jin, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
-
Clin Exp Pediatr. 1990;33(9):1237-1243. Published online September 30, 1990
-
|
In this study we compared between the patients with recurrent gross hematuria (group 1, n=45) and
* with nephrotic range proteinuria (group 2, n=21) in IgA nephropathy who were admitted to Seoul
National University Children’s Hospital during the period from January, 1980 to December, 1989.
The results of the study were as follows.
1) Age of onset and sex ratio were not different between the... |
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-
- A Clinical Study on the Posterior Subcapsular Cataracts in Childhood Nephrotic Syndrome.
-
Dong Kyu Jin, Ja Wook Koo, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jong Hoon Lee, Young Suk Yu
-
Clin Exp Pediatr. 1990;33(8):1097-1103. Published online August 31, 1990
-
|
A clinical study was carried out in 73 children with nephrotic syndrome who had had regular
ophthalmologic examination annually at Seoul National University Children’s Hospital from March
1976 to February 1990 with the aim of finding the relationship between the posterior subcapsular
cataract (PSC) and the effect of corticosteroids. The results were summarized as follows:
1) The number of patients with PSC were 23 cases... |
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-
- Recombinant Human Erythropoietin Therapy in Anemia Accompanied by Chronic Renal Failure.
-
Dong Kyu Jin, Hae Il Cheong, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1990;33(7):970-976. Published online July 31, 1990
-
|
A clinical study was carried out to evaluate the efficacies of rHuEPO (recombinant human
erythropoietin) in anemia of 7 chronic renal failure patients under dialysis at Seoul National
University Children's Hospital from Feb. 1989 to Nov. 1989.
The results were as follows;
- 1) There was progressive increase of hematocrit levels in all 6 hemodialysis patients and mainte-
nance dosage of rHuEPO to sustain hemoglobin... |
-
-
- A Case of Acute Renal Failure Associated with Rhabdomyolysis in Carbon Monoxide Intoxication.
-
Kyung Hee Park, Sei Hee Hwang, Hae Il Cheong, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1990;33(5):690-694. Published online May 31, 1990
-
|
We experienced a case of acute renal failure associated with rhabdomyolysis after Carbon
Monoxide intoxication in a 12 year old Korean girl who had marked soft tissue swelling of the left
thigh, reddish brown colored urine and oliguria.
Diagnosis was made by clinical features, markedly elevated serum muscle enzymes and serum
myoglobin, and Tc 99m-MDP bone scan which revealed increased radioactivity at the left... |
-
-
- Juvenile Nephronophyjisis in An Infant.
-
Young Seo Park, Chang Youn Lee, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Je Geun Chi, Chang Bin Im
-
Clin Exp Pediatr. 1989;32(8):1155-1160. Published online August 31, 1989
-
|
Juvenile nephronophthisis is a chronic tubulo-interstitial renal disease characterized by an early
onset of polyuria and polydipsia, decreased urinary concentrating ability, anemia, growth retardation
and progressive renal disease. It is recognized as an important cause of chronic renal failure in the
childhood. However only one case was reported in the Korean literatures.
In this paper we have reported the second documented case of juvenile... |
-
-
- Urinary Tract Anomalies in Congenital Heart Disease.
-
Chang Youn Lee, Young Seo Park, Hae Il Cheong, Jung Yun Choi, Young Soo Yun, Yong Choi, Kwang Wook Ko, In One Kim, Kyung Mo Yeun, Kwang Myung Kim, Hwang Choi
-
Clin Exp Pediatr. 1989;32(6):804-808. Published online June 30, 1989
-
|
A variety of urinary tract anomalies were detected in 1,569 children with congenital heart disease
during their cardiac evaluation with cardiac cineangiography in the Department of Pediatrics, Seoul
National University Children’s Hospital within a period from October 1985 to April 1988.
The incidence, nature and course of these urinary tract anomalies were analyzed and the results
were as follows;
1) The number of male children... |
-
-
- Cyclophosphamide-Induced Hemorrhagic Cystitis in Acute Lymphocytic Leukemia and Non-Hodgkin Lymphoma.
-
Young Seo Park, Il Soo Ha, Soon Ki Kim, Hae Il Jung, Yong Choi, Hyo Seop Ahn
-
Clin Exp Pediatr. 1989;32(5):665-669. Published online May 31, 1989
-
|
We studied the cyclophosphamide-induced hemorrhagic cystitis in 72 cases of acute lymphocytic
leukemia or Non-Hodgkin lymphoma, which had been treated at Seoul National University Children'
s Hospital from June, 1985 to May, 1988
1) Among 72 cases treated with cyclophosphamide, 6 cases(12.8%) developed hemorrhagic cystitis
in 47 cases of acute lymphocytic leukemia and 2 cases(8.0%) in 25 cases of Non-Hodgkin lymphoma.
2) The development of... |
-
-
- Hypercalciuria in Children with Hematuria.
-
Tae Sung Ko, Chang Youn Lee, Young Seo Park, Hae Il Cheong, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1989;32(5):644-652. Published online May 31, 1989
-
|
Ten children with gross hematuria were diagnosed as hypercalciuria in the Department of
Pediatrics, Seoul National University Children’s Hospital during the period from June 1983 to Aug.
1987. We reviewed their clinical data, retrospectively, and could obtain the following results.
1) The age at the onset of gross hematuria ranged from 4 months to 10 7/12 years, and the male
to female ratio was... |
-
-
- Continuous Arteriovenous Hemofiltration in Children.
-
Hae Il Cheong, Dong Kyu Jin, Young Seo park, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1989;32(2):230-238. Published online February 28, 1989
-
|
Among those who were admitted to the Pediatric Intensive Care Unit (PICU), Seoul National
University Children’s Hospital and developed acute renal failure (ARF) during the disease course, 11
children received continuous arteriovenous hemofiltration (CAVH) by pediatricians during a 3-year-
period from Nov. 85 to Oct. 88. Their clinical findings were analyzed retrospectively, and the results
were as follows;
1) They were 5 boys and 6... |
-
-
- Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children with Cyanotic Congenital Heart Disease.
-
Sang Kyu Park, Hae Il Cheong, Chung Il Noh, Yong Soo Yun, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1988;31(8):1021-1027. Published online August 31, 1988
-
|
PRA’s in peripheral vein, both renal veins, and inferior vena cava (IVC) were measured in 25
normotensive children without renal disease undergoing cardiac catheterization for their underlying
cyanotic congenital heart disease. And we presented the results as reference values/ranges of PRA in
children.
1) There was no significant difference in PRA between both side renal veins at any absolute PRA
levels with a mean ratio (RT/LT)... |
-
-
- Clinical Observation on Hemodialysis in Children with Chronic Renal Failure.
-
Hae Il Cheong, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1988;31(5):590-596. Published online May 31, 1988
-
|
There had been total 21 children with end stage renal disease in whom hemodialysis was done in
the pediatric dialysis unit of Seoul National University Children’s Hospital during the period from
1986. 3. 31 to 1987. 11. 30. And we took a retrospective review of their clinical data, and the results
were as follows
1) Primary glomerular disease, H enoch-Schdnlein nephritis, and reflux nephropathy were... |
-
-
- Acute Tumor Lysis Syndrome in Burkitt Lymphoma.
-
Dong Kyu Jin, Soo Jong Hong, Il Soo Ha, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
-
Clin Exp Pediatr. 1988;31(3):362-369. Published online March 31, 1988
-
|
To assess the tumor lysis syndrome in Burkitt lymphoma, we analyzed the clinical and laboratory
findings of 17 patients with Burkitt lymphoma who were admitted to the Department of Pediatrics,
Seoul National University Hospital from January 1979 to December 1986.
The acute tumor lysis syndrome was diagnosed when two of the five following metabolic abnormal-
ities were met:
① hyperuricemia (≥8.0mg/dl), ② hyperphosphatemia (≥5.5 mg/dl),... |
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-
- A Study on Minimal Change Nephrotic Syndrome in Children.
-
Yong Choi, Hong Jin Lee, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
-
Clin Exp Pediatr. 1988;31(2):220-226. Published online February 28, 1988
-
|
To assess the clinical significance of histopathologic variants of minimal change nephrotic syn-
drome (MCNS) by light microscopic findings, 148 biopsy proven MCNS patients, who were admitted
to Seoul National University Hospital between the period from January 1976 to December 1986, were
analyzed according to clinical findings, steroid responsiveness, and follow up status in relation to the
pathologic variants.
The followings are summary and conclusion.
1) Significantly... |
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-
- Childhood Renal Diseases.
-
Tae Sung Ko, Hae Il Cheung, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1988;31(11):1468-1474. Published online November 30, 1988
-
|
1978년 1월부터 1987년 12월까지 만 10년간 서울대학교 소아병원 소아과에 입원한 환자중 신질환
환아를 대상으로 후향적 인 임상통계학적 고찰을 시 행하여 다음과 같은 결과를 얻었다.
1) 10년기간중 신질환 환아는 총 2,023명으로 이는 동일기간 전체 소아과 입원환아(28,611)의 7.1
%에 해당하였고,전체 환아에 대한 신질환 환아의 비는 매년 거의 일정하였다.
2) 전체 신질환 환아의 남여 비 는 2.2 : 1이 었다.
3) 신증후군(38.8%), 요로감염(18.0%), 급성사구체신염(12.1%) 이 3대 질병을 이루었으며 다음
으로는 반복성 혈뇨(7.6%),... |
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-
- Urinary Red Blood Cell Morphology in Hematuria.
-
Hong Jin Lee, Chang Yeon Lee, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Myung Hee Park
-
Clin Exp Pediatr. 1988;31(11):1460-1467. Published online November 30, 1988
-
|
We have studied morphological alterations in urinary RBC as a tool for the differential diagnosis
of hematuria in children, that is, differentiation of glomerular bleeding from nonglomerular bleeding,
and the results were as follows;
1) Urinary RBCs from glomerular diseases showed higher rate of dysmorphism (84.3±16.8%), and
those from nonglomerular diseases did lower one (15.2 ±12.9%) with phase contrast microscopic
examination.
2) Simple light microscopic examination after Wright’s... |
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-
- A Clinical Observation on Systemic Lupus Erythematosus in Children.
-
Han Wook Yoo, Hae Il Cheong, Hoan Jong Lee, Yong Choi, Kwang Wook Ko, Yong Il Kim
-
Clin Exp Pediatr. 1987;30(5):527-535. Published online May 31, 1987
-
|
To elucidate the clinical characteristics of childhood onset systemic lupus erythematosus (SLE), we
carried out a retrospective review on medical records of sixteen patients who were diagnosed as SLE
on the base of “the 1982 revised criteria for the SLE” (by American Rheumatism Association) at the
Department of Pediatrics, Seoul National University Children’s Hospital between January 1976 and July 1986.
The results were summarized... |
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-
- Pheochromocytoma in Two 10-year Old Children.
-
Young Soo Kim, Young Hoon Kim, Se Won Yang, Yong Choi, Hyung Ro Moon
-
Clin Exp Pediatr. 1987;30(2):207-211. Published online February 28, 1987
-
|
We experienced two cases of pheochromocytoma in 10 year-old boy and girl. Boy had bilateral and
girl had unilateral pheochromocytoma. Both patients who were severely retarded in height growth
had hypertension and one patient had cardiomyopathy. In both patients, vanillylmandelic acid in
urine was increased, and phentolamine test was positive. Adrenal mass was visualized by C.T. in each ease.
Successful surgical removal was done,... |
-
-
- A Case of Potter Syndrome with Bilateral Polycystic Kidneys.
-
Chun Hwa Lee, Jung Hwan Choi, Yong Choi, Chong Ku Yun, Yeon Lim Suh, Je G Chi, Son Moon Shin
-
Clin Exp Pediatr. 1987;30(11):1282-1286. Published online November 30, 1987
-
|
In 1946, Potter described a series of 20 cases of infants in whom bilateral absence of the kidneys was
associated with hypoplasia of the lungs and characteristic faces.
Afterwards it has been known that any condition that causes significant reduction in urine formation or excretion will result in oligohydramnios accounts for many of the nonrenal features of Potter
syndorme. We report a case... |
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-
- Chronic Renal Failure in Children.
-
Yong Choi, Jong Duck Kim, Kwang Wook Ko, Jae Seung Lee, Pyung Kil Kim, Ja Hoon Koo
-
Clin Exp Pediatr. 1986;29(5):493-497. Published online May 31, 1986
-
|
We analyzed data on children with chronic renal failure collected from 36 pediatric training hospitals during the period from Jan. 1, 1980 to Dec. 31, 1984. The following results were obtained:
1) Total number of children with chronic renal failure during the study period was 135. The incidence was about
1 per 2,000 in-patients and 2.09 per million children under 15... |
-
-
- Renovascular Hypertension in Childhood.
-
Jae Won Song, Soo Heun Lim, Yong Choi, Kwang Wook Ko, Chang Yee Hong, Kyung Mo Yeon
-
Clin Exp Pediatr. 1986;29(4):381-386. Published online April 30, 1986
-
|
The following results were obtained from a retrospective analysis of 21 cases of renovascular hypertension who were admitted to Pediatric Department, Seoul National University Hospital, during the period from January 1978 to December 1985. 1) Takayasu arteritis was the most common cause (15 out of 21, 71%), and fibromuscular
dysplasia of renal artery was confirmed only in two (9.5%) cases. 2) Male... |
-
-
- A Clinicopathological Study on the Biopsy-proven Henoch-Schonlein Purpura Nephritis in Children.
-
Jong Yoon Kim, Yong Choi, Kwang Wook Ko, Young il Kim
-
Clin Exp Pediatr. 1986;29(3):265-276. Published online March 31, 1986
-
|
40 patients with Henoch-Schonlein nephritis in whom a per cutaneous renal biopsy was performed at department of pediatrics, Seoul National University Hospital during the periods Jan. 1978-Jan. 1985 inclusive were analyzed in view of clinicopathological correlation.
The results were as follows: 1) Of the 40 patients reviewed, 24 cases were male and 16 female. The mean age of onset was 9 years... |
-
-
- Case Report
- A Case of Dubin-Johnson Syndrome in Childhood.
-
Young Hoon Kim, Young Soo Kim, Sang Kyu Park, Jung Ki Seo, Yong Choi
-
Clin Exp Pediatr. 1986;29(11):1275-1280. Published online November 30, 1986
-
|
A case of Dubin-Johnson syndrome in 10-year-old Korean male child was presented.
The presenting symptom was dark-colored urine for several years. Laboratory findings showed
increased bilirubin, especially direct-reacting bilirubin, and abnormal urinary coproporphyrin pattern (coproporphyrin I : 58%, coproporphyrin JK : 42%). Needle biopsy specimen of liver showed dark-brownish pigmentation in liver cells but was otherwise normal histologically.
|
-
-
- Original Article
- Primary Peritonitis in Children with Nephrotic Syndrome.
-
Hae Il Cheong, Whan Jong Lee, Jeong Kee Seo, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1985;28(7):695-704. Published online July 31, 1985
-
|
Thirty episodes of primary peritonitis in 22 children with nephrotic syndrome who had admitted in the Department of Pediatrics, Seoul National University Hospital from Jan. *81 to Sept. ’84 were studied, and the results were as follows; 1)Among 22 children, male to female ratio was 16 : 6 and the mean age at the onset of
peritonitis was 7.80 years (average... |
-
-
- Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children.
-
Chong Ku Yun, Hae Il Cheong, Chung Il Noh, Jung Yun Choi, Yong Choi, Kwang Wook Ko, Kyung Mo Yeon
-
Clin Exp Pediatr. 1985;28(6):555-563. Published online June 30, 1985
-
|
PRA in peripheral vein, both renal veins and both inferior vena cava (JVC) both proximal and distal to the drainage of the both renal veins was measured in 80 normotensive children with no renal disease undergoing routine cardiac catheterization due to congenital heart disease which did not cause significant hemodynamic changes in most of them. And we presented the results... |
-
-
- Clinical Observation on Hypertension in Hospitalized Children.
-
Chung Il Noh, Jong Yoon Kim, Hea Il Chung, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1985;28(5):477-482. Published online May 31, 1985
-
|
A retrospective study of 234 children with hypertension was done. Those children were selected from the admitted patients to the pediatric ward of SNUH, from Jan. 1 st, 1972 to June 30 th, 1984. Among them, 144(61.5%) exhibited renal diseases, 17(7.3%) endocrine diseases, 15(6.4%) renovascular diseases, 12(5.1%) cardiovascular diseases, 3(1.3%) esstential hypertension, 8(3.5%) miscellaneous casuses. The most common cause among... |
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-
- Captopril in Children with Renovacular Hypertension.
-
Yong Choi, Hoan Jong Lee, Hee Young Shin, Kwang Wook Ko, Chang Yee Hong
-
Clin Exp Pediatr. 1985;28(1):58-67. Published online January 31, 1985
-
|
Captopril, a kind of converting enzyme inhibitors, is a promising anti-hypertensive drug, which is developed recently, and studied mainly in adult patients. We administered captopril to 4 children with renovascular hypertension, three of them accompanied Takayasu's arteritis and the remainder had isolated lesion. Three to five times of initial trials were performed on each patient with 12.5 mg of captopril.... |
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-
- Idiopathic Membranoproliferative Glomerulonephritis in Children.
-
Hae Il Cheong, Hee Shang Youn, Whan Jong Lee, Yong Choi, Kwang Wook Ko, Yong Il Kim
-
Clin Exp Pediatr. 1985;28(1):45-57. Published online January 31, 1985
-
|
Among total 452 children with percutaneous kidney needle biopsy due to renal disease in the Department of Pediatric, Seoul National University Hospital, from Jan. 75 to Nov.84, 20(4.4%) were confirmed as
embranoproliferative glomerulonephritis(MPGN) histopathologically. And 4 out of these 20 were excluded from this report because of association of systemic disease. A review of clinical and pathological findings of the... |
-
-
- Case Report
- Rifampin Induced Nonresponsiveness to Steroid Therapy in Children with Minimal Change Nephrotic Syndrome .
-
Hae Il Cheong, Sang Bok Suk, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1984;27(5):506-510. Published online May 31, 1984
-
|
We experienced three children with the biopsy proven minimal change nephrotic syndrome who had failed to respond to prednisolone, 60 mg/m2/d for 4 to 9 weeks due to concomittent administration of rifampin.
Because rifampin is a known enzyme inducer of the liver like phenobarbital and dilantin which can increase the clearance of the other drugs such as steroid etc., rifampin were... |
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-
- Acute Tumor Lysis Syndrome.
-
Sun Oak Park, In Sil Lee, Hyp Seop Ahn, Yong Choi
-
Clin Exp Pediatr. 1984;27(3):303-312. Published online March 31, 1984
-
|
To assess the incidence and the effectiveness of preventive measures for tumor lysis syndrome, we analyzed the serial electrolytes levels in leukemia (Group A, 15 patients) and in lymphoma (Group B, 8 patients) patients.
The results were 1)Serum LDH were elevated in all of the patients before the chemotherapy. 2)Serum uric acid were also elevated in 8 patients (A 5, B... |
-
-
- Original Article
- Clinical Observation about complications(Especially about Mortality Cases) in Childhood Primary Nephrotic Syndrome.
-
Hae ll Cheong, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1984;27(3):246-252. Published online March 31, 1984
-
|
Among 350 children who had been admitted to the Ward of Pediatrics, Seoul National University Hospital during the period from 1975.1.1. to 1983.12.31. and had been diagnosed as idiopathic nephrotic syndrome, total 21 cases (6%) had expired or had progressed into end stage renal disease during follow-up. Among these, 13 cases(61.9%; Group A) had expired due to chronic renal failure... |
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-
- Clinical Significance of Selectivity Index in Nephrotic Syndrome.
-
Hoan Jong Lee, Hee Jin Kim, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1984;27(1):68-73. Published online January 31, 1984
-
|
Slectivity I nd ices (CIgG/Ctransf erri n) of 114 nephrotic children, who were admitted to the Pediatric ward of SNUH from January, 1979 to December 1982, were, analyzed in relation to pathology, response to steroid treatment and the variability in the individual patients. In Summary 1)83% of MPGN, and 74% of FSGS showed S.I of more than 0.2 while 36%... |
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-
- Statistical Observation for Pediatric Inpatients.
-
Keun Chan Sohn, Sung Sook Cho, Kwang Chan Doh, Yong Choi, Ki Sub Chung, Dong Hyuk Kum, Sung Taek Kim
-
Clin Exp Pediatr. 1984;27(1):1-8. Published online January 31, 1984
-
|
We observed patients admitted to the department of Pediatrics of 24 general hospitals in Korea during the past five years from Jan. 1976 to Dec. 1980 and classified them, by year & disease according to the International Classification of Disease by W.H.O.(1965 Revision). The results were as follows: 1)The total number of pediatric inpatients was 138,136 with about 10% yearly... |
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-
- Renal Disease in Children-A Ten-Years Experience.
-
Hee Young Shin, Hae Il Cheong, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1983;26(7):681-686. Published online July 31, 1983
-
|
Statistical analysis of inpatients of Seoul National University Hospital from 1972 to 1981
who had renal diseases was performed with respect to their disease pattern, annual incidence
of each disease, and age distribution.
From 1972 to 1981 renal disease was found in 831 patients among 11,226 total inpatients
(7.4%). Male to female ratio of renal disease patients was 2.2 to 1, while male to... |
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-
- Clinical Observation of Juvenile Diabetes Millitus.
-
Hae Il Cheong, Dong Gyoon Kim, Yong Choi, Kwang Wook Ko
-
Clin Exp Pediatr. 1983;26(6):553-563. Published online June 30, 1983
-
|
Clinical data of 33 children with juvenile diabetes mellitus who were admitted to the Seoul
National University Hospital from Jan. 1967 to Feb. 1983 were analyzed retrospectively.
Male to female ratio was 10:23, the mean age at onset was 6 10/12 years, and there was
considerable seasonal variation with peaks in late winter and spring.
Polyuria and polydipsia were noted in all cases as... |
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-
- Case Report
- A Case Report Kostmann Syndrome.
-
Han Wook Yoo, Son Moon Shin, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
-
Clin Exp Pediatr. 1983;26(3):284-288. Published online March 31, 1983
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|
Kostmann syndrome (Infantile genetic agranulocytosis), a disease characterized by recurrent
infections leading to death in infancy, shows an agranulocytosis with variable monocytosis,
eosinophilia in the peripheral blood, accompanied by the maturation arrest of the myelocytic
series at the promyelocyte-myelocyte level.
A 2 years 3 month old female patient with Kostmann syndrome is reported, who has
suffered from recurrent infections since 1 month of age. During... |
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-
- Original Article
- Lipoprotein Profiles in Minimal Change Nephrotic Syndrome.
-
Yong Choi, Heui Jeen Kim, Hae Il Cheong, Jeong Kee Seo, Kwang Wook Ko
-
Clin Exp Pediatr. 1983;26(3):237-246. Published online March 31, 1983
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Data obtained from 59 hospitalized patients with minimal change nephrotic syndrome which
was confirmed by kidney biopsy, were analyzed for serum albumin, serum lipids, 24hr urine
protein, creatinine clearanee, HDL-eholesterol. In 38 of the patients, lipoproteins were analyzed.
The following results were obained
1. Serum phospolipid (PL) was increased whenever serum total cholesterol (TC) was
increased but to a lesser degree. The ratio of TC/PL were... |
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- Case Report
- Pancreatic Pseudocysts and Ascites as Complications of Chronic Pancreatitis.
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Nam Su Kim, Hee Ju Kim, Kyoo Duck Lee, Yong Choi, Hyung Ro Moon
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Clin Exp Pediatr. 1982;25(2):183-189. Published online February 28, 1982
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A case of pancreatic pseudocysts and bloody pancreatic ascites as complications of chronic pancreatitis in eleven-year-old girl was reported. She was admitted to the pediatric ward with chief complaints of abdominal distension and bloody ascites. About nine months prior to admission, when she was stuck by a bicycle, she had sustained a blow on her abdomen. She has been apparently... |
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- Original Article
- Pericardial Effusion in Patients with Rheumatic Fever.
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In Suck Seo, Hee Ju Kim, Jae Ho Lee, Yong Soo Yoon, Yong Choi, Chang Yee Hong
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Clin Exp Pediatr. 1982;25(12):1225-1233. Published online December 31, 1982
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Pericarditis denotes worse prognosis in patients with rheumatic fever. During the period of
4 years from Jan. 1978 to Dec. 1981, one hundred and eighteen patients were diagnosed as
rheumatic fever on the basis of revised Jones* criteria. One hundred and one patients of
them were evaluated with M-mode echocardiography, and were analysed according to Horo-
witz^ classification of pericardial effusion.
The results were as... |
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- The Incidence of HBs Antigenemia in Glomerular Desease and Control Group in Children.
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Yong Choi, Whan Jong Lee, Jeong Kee Seo, Kwang Wook Ko
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Clin Exp Pediatr. 1981;24(2):122-127. Published online February 15, 1981
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HBsAg, HBcAb and HBsAb were examined with radio-immunoassay in 265 patients with glomerular disease, who were admitted to wards or visited to outpatient clinics of department of pediatrics, Seoul National University Hospital, from Jan., 78 to Oct. 80, and in 576 control group, with other than liver disease and without history of transfusion. The incidence in glomerular disease was 10.2%(27... |
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- Case Report
- Late Hemorrhagic Disease of Infancy.
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Joong Gon Kim, Young Min Ahn, Hyo Seop Ahn, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1980;23(7):572-577. Published online July 15, 1980
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A hemorrhagic disease due to prothrombin complex deficiency os described in 4 infants from 1 to 11 months of age. This disease is different from the hemorrhagic disease of the newborn. The main differences are that it is found in an older age group and that intracranial hemorrhages are frequent. Rapid clinical and laboratory response after vitamin K therapy are... |
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- Original Article
- Long Term Follow-up Study of Chidren with nephrotic Syndron (over 5years).
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Hae Il Cheong, Whan Chong Lee, Yong Choi, Cwang wook Ko
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Clin Exp Pediatr. 1980;23(2):130-142. Published online February 15, 1980
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Follow-up study of fifty two children with nephrome who had once admitted to the pediatric ward of S.N.U.H were presented with regards to response to initial steroid therapy, relapsing patterns, and factors affecting prognosis. All patients were followed up for more than 5 years and the mean period of follow-up was 7 7/12 years, and in two patients, follow-up for... |
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- Case Report
- A Case of Chylous Ascites in an Infant Boy.
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Kyu Chan Kim, Hae Il Cheong, Yong Choi, Hyung Ro Moon
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Clin Exp Pediatr. 1980;23(1):63-67. Published online January 15, 1980
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The authors report a case of chylous ascites in a two month old boy with massive ascites. He was managed with repeated therapeutic paracentesis and skimmed milk feeding. A marked improvement was resulted in clinical symptoms and laboratory findings at the time of discharge to be followed-up at the outpatient service. A brief review of literatures is included |
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- Original Article
- Statistical Analyses of the Diseases of the Nervous system: With Special Reference to the Annual Change of the Incidence.
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Yong Seung hwang, Yong Choi, Dwang Wook Ko
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Clin Exp Pediatr. 1980;23(1):41-56. Published online January 15, 1980
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Primary disorders of the nervous system admitted to the Pediatric ward of Seoul National University Hospital during 10 years from January 1969 till December 1978 were analysed to observe particularly the annual change of the incidence. Total number of the diseases of the nervous system was 1522, about 20.2% of the total admitted patients during this period. Annual incidence of... |
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- Clinical Assessment on Juvenile Diabetes Mellitus.
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Sang Bok Suk, Hyo Sup Ahn, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1979;22(3):223-233. Published online March 15, 1979
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Eleven cases of juvenile diabetes mellitus who were admitted Seoul National University Hospital from Jan., 1969 to Aug., 1978 were aha1yzed. The mean age of onset was 7 and female to male ratio was 8 to 3 with female preponderance. Four had family history of diabetes, although none had diabetic sibling. Polyuria and polydipsia were noted in all cases as... |
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- Clinical Assessement of Chronic Renal Failure(CRF).
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Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1977;20(4):256-264. Published online April 30, 1977
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The following results were obtained on clinical assessment to 11 cases of CRF who had been admitted to the Dept. of Pediatrics, SNUH, during the period from Sept., 1970 to Jan., 1977. 1. Age and sex ratio: Two cases were below 5 years old, the other two being between 5 and 10 years old, however, most cases (7 out of... |
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- 24 hour Urinary Excretion of Creatinine, Phosphorus Nitrogen, Na, K and Cl During the Neonatal Period.
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Yong Choi
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Clin Exp Pediatr. 1977;20(3):205-210. Published online March 31, 1977
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According to the concept of alteration in structure and function to meet the needs of organism, the kidney function develops rapidly after the delivery. Until 2 years of age, however, there are still functional and anatomical immaturities in the neonatal Kidney. The rates of glomerular filtration in the neonates are only 30~50% of those observed in adults. The tubules are... |
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- Case Report
- DiGeorge Syndrome
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Tae Woon Kim, Yong Choi, Hyung Ro Moon
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Clin Exp Pediatr. 1976;19(5):366-371. Published online May 31, 1976
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A case of DiGeorge syndrome in 2-month-old male infant was presented with a brief review of literature.
He was characterized by a malformed right ear, a short philtrum of the upper lip, polydactyly, hypocalcemia, generalized, convulsions and absence of the thymic shadow in a film of the chest. Although the generalized convulsions were abated with calcium gluconate therapy, he died on... |
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- Original Article
- Follow-up Study of Children with Nephrotic Syndrome
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Jeong Kee Seo, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1976;19(12):893-903. Published online December 31, 1976
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Forty seven children with nephrotic syndrome were studied. No specific cause for nephrotic syndrome was found in all children except one with tridione induced nephrotic syndrome. Response to the initial continuous steroid therapy, relapsing patterns and factors affecting prognosis were evaluated in this study. All patients were followed up for more than 3 years. The mean period of observation was... |
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- Case Report
- A Case of Chronic Atrial Tachycardia
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Hyo Seop Ahn, Yong Choi, Tae Woon Kim, Chong Ku Yoon, Chang Yee Hong, Johng Kun Ahn
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Clin Exp Pediatr. 1974;17(2):149-153. Published online February 28, 1974
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A case of chronic atrial tachycardia in a 1 1 year and 10 month-old boy is reported.
The patient was admitted with the chief complaints of palpitation and chest discomfort
Tachycardia persisted till discharge but subjective symptoms were disappeared. Digitalis therapy
provoked partial AV block and decreased ventricular rate.
Auricular rate was also slightly decreased.
The review of literature was made briefly.
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- Original Article
- Clinical Assessment of Nephrotic Syndrome
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Yong Choi, Sang Man Shin, Chong Koo Yun, Kwang Wook Ko
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Clin Exp Pediatr. 1973;16(2):130-136. Published online February 28, 1973
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The following results were obtained on clinical assessment to 50 cases of nephrotic syndrome who had been admitted to the Dept, of Pediatrics, SNUH, during the period from Jan., 1964 to Sept.1971. 1.Age of onset: The fifty percentage of the cases were found between 2 and 5 years old, with the average age of onset of 6 years.
2.Sex ratio: :Male... |
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- Case Report
- Neuromyelitis Optica
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Soo Young Pi, Don Hee Ahn, Yong Choi, Sang Hyup Kim
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Clin Exp Pediatr. 1972;15(3):232-234. Published online March 31, 1972
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A Case of c'inically typical neuromyelrtis optica is reported. The patient was 6 year-old-boy who was
admitted to our hospital due to sudden loss of visual acuity and ascending paraplegia for 7 days
duration on April-4th, 1970.
Transient recovery of visual acuity and imp roverment of muscle power occured about 2 weeks after
the onset, butthey were aggravated again 1 week later, and remained... |
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